Ramasamy Pandian       

Ramasamy Pandian, PhD

Research Scientist
Department of Internal medicine
Dorothy M. Davis Heart & lung Research Institute
Ohio State University Medical Center
420 W 12th Avenue, Room 180
Columbus OH 43210
Phone: (614) 292-7880
Email: pandian.6@osu.edu
 
Research Interests
  • Development of crystalline lithium napthalocyanines based oxygen sensors
  • Noninvasive measurement of oxygen by EPR oximetry
  • Nanoparticulate probe for in vivo monitoring of tissue oxygenation
  • Magnetic resonance contrast agent development
  • Nitric oxide sensing by EPR spectroscopy
  • Photodynamic therapy
 
Current Projects
  • Development of perchlorotriphenylmethyl radical probes for quantification of oxygen and superoxide in biological systems
  • Development of an implantable polymer membrane encapsulated paramagnetic probes for oxygen-sensing applications
  • Synthesis of nanoparticles of oxygen sensors coated with flurophores for targeted determination of oxygen levels in vivo and in vitro.
 
Selected Publications
  • R.P. Pandian, G. Meenakshisundaram, A.Bratasz, E. Eteshola, S.C. Lee and P. Kuppusamy. An implantable Teflon chip encapsulating lithium naphthalocyanine microcrystals for secure, safe, repeated measurements of local pO2 in tissues. To be submitted to Biosens. Bioelectron., 2009
  • R.P. Pandian, M. Dolgas, C. Marginean, P.M. Woodward, P. Chris Hammel, P.T. Manoharan, and P. Kuppusamy. Molecular packing and magnetic properties of a new lithium naphthalocyanine crystal: Hollow channels enabling permeability and paramagnetic sensitivity to molecular oxygen, J. Mater. Chem., (Accepted 2009)
  • E. Ethesola, R.P. Pandian and S. Lee and P. Kuppusamy. Polymer coating of paramagnetic particulates for in vivo oxygen-sensing applications. Biomedical Microdevices, (Accepted 2009)
  • M. Salva, R.P. Pandian, P. Kuppusamy and G. Agarwal. Magnetic force microscopy of an oxygen sensing spin-probe. Israel Journal of Chemistry, 2008, 48, 33-38
  • R. P. Pandian, M. Dolgos, V. Dang, J.Z. Sostaric, P.M. Woodward and P. Kuppusamy. Structure and oxygen-sensing paramagnetic properties of a new lithium 1,8,15,22-tetraphenoxyphthalocyanine radical probe for biological oximetry, Chem. Mater., 2007, 19, 3545-3552
  • R.P. Pandian, K. YoungI1, P.M. Woodward, J.L. Zweier, P.T. Manoharan and P. Kuppusamy. Open molecular framework in lithium octabutoxy-naphthalocyanine paramagnetic crystal: implications for the detection of oxygen and nitric oxide by EPR spectroscopy J. Mater. Chem., 2006, 16, 3609- 3618

Last update: Feburary 2009. All rights reserved 2008-2010.