Periannan Kuppusamy       

Periannan Kuppusamy, PhD

Associate Professor of Internal Medicine
Director, Biomedical EPR Imaging Center
Department of Internal medicine
Dorothy M. Davis Heart & lung Research Institute
Ohio State University Medical Center
420 W 12th Avenue, Room 114
Columbus OH 43210
Phone: (614) 292-8998
Email: periannan.kuppusamy@osumc.edu
 
Research Interests
Detection and imaging of free radicals; myocardial ischemia-reperfusion injury; antioxidants; noninvasive measurement and imaging of oxygen, metabolism and redox status in tissues; tumor physiology
 
Current Projects
  • Stemcell therapy
  • HBC heart
  • HBC cancerI
 
Selected Publications
  • Sendhil Velan, S., Spencer, R. G. S., Zweier, J. L., and Kuppusamy, P. Electron paramagnetic resonance oxygen mapping: Direct visualization of oxygen concentration in tissues. Magn. Reson. Med. 43, 804-809 (2000)
  • Li, H., Xu, K. Y., Zhou, L., Kalai, T., Zweier, J. L., Hideg, K. and Kuppusamy, P. A Pyrroline derivative of mexiletine offers marked protection against ischemia/reperfusion-induced myocardial contractile dysfunction. J. Pharmacol. Exp. Therap. 295, 563-571(2000)
  • Kuppusamy, P., Shankar, R. A., Roubaud, V. M., and Zweier, J. L. Whole Body Detection and Imaging of Nitric Oxide Generation in Mice Following Cardiopulmonary Arrest: Detection of Intrinsic Nitrosoheme Complexes. Magn. Reson. Med. 45, 700-707(2001)
  • Ilangovan, G., Manivannan, A., Li, H., Yanagi, H., Zweier, J. L., and Kuppusamy, P. A new naphthalocyanine-based EPR oximetry and imaging probe for biological applications. Free Radic. Biol. Med. 32, 139-147 (2002)
  • Kuppusamy, P., Li, H., Ilangovan, G., Cardounel, A. J., Zweier, J. L., Yamada, K., Krishna, M. C., and Mitchell, J. B. Noninvasive imaging of redox status in tumor: Effect of tissue glutathione levels in a RIF-1 tumor model. Cancer Research 62, 307-312 (2002)
 
Selected Presentations
  • Who to write a manuscript
  • Priciples ofEPR Imaging
  • EPR Oximetry
 
Hobbies
Tamil Script
 
CV, NIH Biosketch

Last update: Feburary 2009. All rights reserved 2008-2010.