Muthulakshmi Kuppusamy

Research Associate
Department of Internal medicine
Dorothy M. Davis Heart & lung Research Institute
Ohio State University Medical Center
420 W 12th Avenue, Room 114
Columbus OH 43210
Phone: (614) 292-8998
Email: muthulakshmi.kuppusamy@osumc.edu

Research Interests

I work primarily in the area of isolation, culture and maintenance of different cell types including stem cells, cancer cells, endothelial cells and smooth muscle cells. I belong to the stem cell therapy group which uses stem cells such as skeletal myoblasts (mice and rats) for implantation and therapy for myocardial infarction. I also use protein assays such as western blot. I am also involved in cell culture and providing cells to Dr. Parinandi and his lab. I was also a part of the organizing committee for EPR 2005.

Selected Publications

Selvendiran K, Bratasz A, Kuppusamy ML, Brian R and Kuppusamy P (2008). Phosphorylated STAT3 is activated by Induction of Reactive Oxygen Species in Ovarian Cancer Cells Cultured under Hypoxic Conditions. (In Preparation for Cancer Research).
Selvendiran K, Kuppusamy ML, Bratasz A, Tong L, Rink C, Sen CK, Kalai T, Hideg K Brian R and Kuppusamy P (2008). Inhibition of vascular smooth muscle cell proliferation and restenosis by a curcuminoid through up regulation of PTEN. Arteriosclerosis, Thrombosis and Vascular Biology (Under Review)
Khan M, Kutala VK, Wisel S, Chacko SM, Kuppusamy ML, Kwiatkowski P, Kuppusamy P. Measurement of in situ myocardial tissue pO2 after stem cell therapy using oxygen sensing probe by EPR spectroscopy. Adv. Exp. Med. Biol. 614: 45-52, 2008.
Chacko M, Khan M, Kuppusamy ML, Kuppusamy P. “Monitoring of tissue oxygenation and functional improvement in a rat model ofacute myocardial infarction (AMI) treated with stem cells”. Am J physiol Heart Circ Physiol, 2008, Communicated.
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