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Mahmood Khan, PhD |
Assistant Professor
Department of Internal medicine
Division of Cardiovascular Medicine
Dorothy M. Davis Heart & lung Research Institute
Ohio State University Medical Center
420 W 12th Avenue, Room 116A
Columbus OH 43210
Phone: (614) 292-8383
Email: Mahmood.khan@osumc.edu |
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- Stem cell therapy (MSCs) for myocardial infarction
- Hyperbaric oxygen (HBO) therapy after stem cells transplantation in the infarct heart
- Development of rodent models for myocardial infarction and hypertrophy
- Evaluating newer cardiovascular drugs by inducing ischemia-reperfusion injury to the heart in both ex vivo and in vivo models
- Measurement of myocardial oxygenation after stem cell therapy using EPR spectroscopy
- Echocardiography in rodents
- Oxidative stress and measurement of free radicals in the heart
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- Stem cell therapy
- Hyperbaric oxygen therapy
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- Khan M, Varadharaj S, Latha P. Ganesan, Jagdish C. Shobha, Maddireddi U. Naidu, NarasimhamL. parinandi, Susheela Tridandapani, Vijay Kumar Kutala, Periannan Kuppusamy. “C-phycocyanin protects against ischemia – reperfusion injury of heart through involvement of p38 MARK and ERK signaling”. Am J physiol Heart Circ Physiol,, 290:H2136-H2145, 2006.
- Khan M, Kutala VK, Vikram DS, Wisel S, Chacko SM, Kuppusamy ML, Mohan IK, Zweier JL, Kwiatkowski P., Kuppusamy P. “Skeletal myoblasts transplanted in the ischemic myocardium enhances in situ tissue oxygenation”, Am J physiol Heart Circ Physiol 293, 2007
- Khan M, Mohan IK, Kutala KV, Kotha S, Parinandi NL, Hamlin RL Kuppusamy P. “Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS leading to enhancement of nitric-oxide bioavailability and tissue oxygen”. Antioxidants and Redox signaling, Oct 2008.
- Khan M, Mohan IK, Wisel S, Selvendiran K, Sridhar A, Carnes CA, Bognar B, Kálai T, Hideg K ., Kuppusamy P. “Cardioprotection by HO-4038, a Novel Verapamil Derivative, Targeted against Ischemia and Reperfusion-mediated Acute Myocardial Infarction”. Am J physiol Heart Circ Physiol. Jan; 296(1):H140-51, 2009
- Khan M, Wisel S, Kuppusamy ML, Mohan IK, Chacko SM, Rivera BK, Sun B, Hideg K, Kuppusamy P. “Pharmacological preconditioning of mesenchymal stem cells with Trimetazidine protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression”. Journal of Pharmacology and Experimental Therapeutics. Feb 2009.
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| Soccer, volleyball, and cricket. |
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| CV, NIH Biosketch |
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| Last update: Feburary 2009. All rights reserved 2008-2010. |
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