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Anna Bratasz, PhD |
Department of Internal medicine
Dorothy M. Davis Heart & lung Research Institute
Ohio State University Medical Center
420 W 12th Ave, Room 126
Columbus OH 43210
Phone: (614) 688-8068
Email: Bratasz.1@osu.edu |
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- In vivo EPR and MRI imaging
- Development of EPR-imaging application for tumor tissue using magnetically labeled cells and evaluation of the spatial distribution of oxygen concentration in the tumor
- Development of noninvasive measurement of oxygen
- Mechanism of drug resistance
- Cancer therapy
- Degenerative diseases
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- Anticancer therapy (including anti-vascular therapy)
- MRI study of cancer physiology
- EPR oximetry
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- Anna Bratasz, Nathan M. Weir, Narasimham L. Parinandi, Jay L. Zweier, Rajagopalan Sridhar, Louis J. Ignarro, Periannan Kuppusamy, Reversal to Cisplatin Sensitivity in Recurrent Human Ovarian Cancer Cells by NCX-4016, a Nitro-derivative of Aspirin, Proc. Nat. Academy of Sciences, 2006, 103(10): 3914-3919
- Bratasz Anna, Aditi Kulkarni, Periannan Kuppisamy, Perchlorotriphenylmethyl Radical in Hexafluorobenzene: An Injectable Probe Formulation for Imaging of Oxygen Concentration in Tumors, Biophysical Journal, 2007,92(8):2918-25
- Anna Bratasz, PhD, Yuanmu Deng, PhD, Ramasamy P. Pandian, PhD, John D. Grecula, MD, Nilendu Gupta PhD, Periannan Kuppusamy, PhD, In Vivo Monitoring and Imaging of Changes in pO2 at the cellular levels in RIF-1 Tumor as a Function of growth and post-irradiation, Magnetic Resonance in Medicine, 2007, 57(5):950-959
- Karuppaiyah Selvendiran, Anna Bratasz, Liyue Tong, and Periannan Kuppusamy, NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 Signaling and Modulates Bcl-2 Proteins in Cisplatin-Resistant Human Ovarian Cancer Cells and Xenografts, Cell Cycle, 2008, 7(1):81-88
- Galina I. Roshchupkina, Andrey A. Bobko, Anna Bratasz, Vladimir A. Reznikov, Periannan Kuppusamy, and Valery V. Khramtsov, In Vivo Electron Paramagnetic Resonance Measurement of Glutathione in the Tumor-Bearing Mice Using Improved Disulfide Biradical Probe, Free Radical Biology & Medicine, 2008, 45(3): 312-320
- Anna Bratasz, Karuppaiah Selvendiran, Tomasz Wasowicz, Andrey Bobko, Valery V Khramtsov, Louis J Ignarro, and Periannan Kuppusamy, NCX-4040, an NO-releasing aspirin derivative, induces apoptosis and further sensitizes cisplatin-resistant human ovarian xenograft tumors to cisplatin by depletion of intracellular thiols, J. Trans. Med., 2008, 6:9
- Monograph: S. Lukiewicz, M. Elas, J. Raczek, A. Bratasz, S. Pajak, K. Cieszka, EPR signals detectable in human tumors, Ch.23, Nitric Oxide in Transplant Rejection and Anti-tumor Defense, Eds. S. Lukiewicz, J.L. Zweier, Kluwer Academic Publisher, USA, 1998, pp. 353-370
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| CV, NIH Biosketch |
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| Last update: Feburary 2009. All rights reserved 2008-2010. |
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